A soul can be bent, broken, twisted and warped and tempted beyond all recognition, but it cannot be destroyed; Anna knows this, deep in her heart where she knows the Alleluia and the light of Grace, and so when Ruby dies by her own knife it does not take her long to track down the Reaper: "Tessa," she says, "I call you by your human name as you call me by mine, and I ask you for your help in finding another, who was human once and will answer to that name still: I ask you for the path that goes Beyond."
my reaction to the last couple episodes of S4
THEN ANNA PULLS A CASTIEL AND GETS RUBY BACK.